NAD Intravenous Infusions

For IV infusion, the preferred form is NAD⁺ (Nicotinamide Adenine Dinucleotide in its oxidized form).

Why is NAD⁺ Used for IV Therapy?

• Direct Bioavailability: NAD⁺ can be directly utilized by cells without requiring conversion from another form like NADH.
• Energy and Mitochondrial Support: Boosts ATP production, helping with energy metabolism, cognitive function, and cellular repair.
• Anti-Aging and Detoxification: Used in wellness clinics for potential benefits in aging, neuroprotection, and recovery from addiction or stress.

Why Not NADH for IV?

• NADH is less stable and harder to administer effectively via IV.
• It must first be converted back into NAD⁺ before cells can efficiently use it in metabolic pathways.

Potential Benefits of NAD⁺ IV Therapy

• Increased energy and reduced fatigue
• Improved mental clarity and cognitive function
• Enhanced cellular repair and anti-aging effects
• Potential neuroprotective benefits (e.g., for brain fog, Alzheimer’s, or Parkinson’s)

NAD⁺ IV Therapy: Dosage, Benefits, and Risks

Dosage and Administration

• Standard Dosage: Typically ranges from 250 mg to 750 mg per session, depending on the individual’s needs.
• Infusion Time: Usually takes 2 to 4 hours to prevent side effects like nausea or flushing.
• Frequency:
  • For general wellness: Once a week or biweekly
  • For anti-aging or cognitive enhancement: Multiple sessions over several weeks
  • For addiction recovery: Daily infusions for 3–10 days, then maintenance doses
• Customization: Some clinics offer tailored IV drips with vitamins (B-complex, C) or amino acids for enhanced effects.

Potential Benefits

• Energy Boost – Supports mitochondrial function and ATP production, reducing fatigue.
• Cognitive Enhancement – May improve mental clarity, memory, and focus.
• Anti-Aging & Cellular Repair – Helps DNA repair and sirtuin activation (linked to longevity).
• Neuroprotection – May benefit brain health in conditions like Alzheimer’s and Parkinson’s.
• Mood & Mental Health – Some evidence suggests NAD⁺ can help with anxiety and depression.
• Detox & Addiction Recovery – Used in addiction treatment centers for opioid, alcohol, and stimulant withdrawal.

Risks and Side Effects

• Mild Side Effects (if infused too fast):
  • Nausea
  • Flushing/warmth
  • Headaches
  • Dizziness
  • Cramping
• Serious Risks (Rare):
  • Rapid heart rate or palpitations
  • Drop in blood pressure
  • Allergic reaction (very uncommon)

To minimize side effects, infusions are done slowly and sometimes combined with hydration.