Covid19 Cytokine Storm

Researchers are identifying exactly which cytokines (inflammation causing chemicals) are primarily responsible for signaling the storm of inflammation that comes in the later phases of Covid19 infection, namely tumor necrosis factor alpha (TNF alpha) and interferon gamma (IFN gamma).  By suppressing these two cytokines in their research subjects the inflammation storm was effectively stopped.

Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes

From the authors “Collectively, our findings suggest that blocking the cytokine-mediated inflammatory cell death signaling pathway identified here may benefit patients with COVID-19 or other infectious and autoinflammatory diseases by limiting tissue damage/inflammation.”

Supplements to lower cytokines

The conventional medication used to lower inflammation is a steroid.  Used in the ICU as well as in outpatient settings, we routinely use steroids to quell life threatening inflammation.

There are numerous natural compounds that also suppress these two cytokines.

Both – turmeric/curcumin, fish oil, EGCG (green tea extract)

TNF alpha – NAD, PQQ

IFN gamma -boswellia, andrographis, resveratrol, olive leaf extract

 

 

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