Ketamine

Intravenous Ketamine is proving to be a tremendous treatment for intractable depression as well as chronic pain.  About half the patients treated respond positively with results lasting up to a week in most of the responders.

It has emerged as a treatment option for a variety of chronic pain conditions including fibromyalgia, small fiber neuropathy, Complex Regional Pain Syndrome (CRPS), Reflex Sympathetic Dystrophy (RSD) and psychiatric conditions including depression, Post Traumatic Stress Disorder (PTSD), suicidal ideation, and Obsessive-Compulsive Disorder (OCD).

Ketamine in the News

Remarkable secrets of ketamine’s antidepressant effect unlocked by scientists

https://www.independent.co.uk/news/health/ketamine-antidepressant-brain-scientists-psychiatrists-nature-depression-suicidal-thoughts-mood-a8212936.html

Could Party Drug Ketamine Be a Treatment for Depression?

https://www.rollingstone.com/culture/features/ketamine-future-of-depression-treatment-w488998

‘The fog is gone’: How ketamine could help lift hard-to-treat depression

https://www.ctvnews.ca/health/the-fog-is-gone-how-ketamine-could-help-lift-hard-to-treat-depression-1.3784490

Ketamine Research

Ketamine for Depression, 1: Clinical Summary of Issues Related to Efficacy, Adverse Effects, and Mechanism of Action.

https://www.ncbi.nlm.nih.gov/pubmed/28448702

Ketamine safety and tolerability in clinical trials for treatment-resistant depression.

https://www.ncbi.nlm.nih.gov/pubmed/25271445

Low-dose ketamine for treatment resistant depression in an academic clinical practice setting.

https://www.ncbi.nlm.nih.gov/pubmed/28666206

Symptomatology and predictors of antidepressant efficacy in extended responders to a single ketamine infusion.

https://www.ncbi.nlm.nih.gov/pubmed/27839782

How does ketamine elicit a rapid antidepressant response?

https://www.ncbi.nlm.nih.gov/pubmed/25462290

The use of ketamine as an antidepressant: a systematic review and meta-analysis.

https://www.ncbi.nlm.nih.gov/pubmed/25847818

Ketamine for rapid reduction of suicidal ideation: a randomized controlled trial.

https://www.ncbi.nlm.nih.gov/pubmed/26266877

Do the dissociative side effects of ketamine mediate its antidepressant effects?

https://www.ncbi.nlm.nih.gov/pubmed/24679390

Rapid and longer-term antidepressant effects of repeated ketamine infusions in treatment-resistant major depression.

https://www.ncbi.nlm.nih.gov/pubmed/22840761

Ketamine Brochure

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